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  Stiff-person syndrome (SPS) is a rare neurological disorder that affects approximately one in a million people. The condition causes muscle stiffness and spasms, which can lead to difficulties with movement and the ability to carry out everyday activities. SPS is believed to be an autoimmune disorder, meaning that the immune system attacks healthy cells in the body. In the case of SPS, the immune system attacks the cells that control muscle movement, leading to the stiffness and spasms characteristic of the condition. One of the main symptoms of SPS is muscle stiffness, which can affect any part of the body but is most commonly felt in the trunk or back. This stiffness can cause a person to feel as if they are locked in position, unable to move or change position. The muscle stiffness in SPS can be accompanied by painful muscle spasms, which can be triggered by a variety of factors, including stress, loud noises, or sudden movements. These spasms can further restrict movement an...